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Tom Cruise
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Ethan Hunt
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Philip Seymour Hoffman
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Owen Davian
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Ving Rhames
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Luther Stickell
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Billy Crudup
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John Musgrave
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Michelle Monaghan
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Julia Meade
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Jonathan Rhys Meyers
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Declan Gormley
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Keri Russell
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Lindsey Farris
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Maggie Q
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Zhen Lei
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Simon Pegg
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Benjamin 'Benji' Dunn
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Eddie Marsan
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Brownway
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Laurence Fishburne
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Theodore Brassel
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Bahar Soomekh
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Davian's Translator
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Jeff Chase
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Davian's Bodyguard
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Michael Berry Jr.
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Julia's Kidnapper
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Carla Gallo
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Beth
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Bellamy Young
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Rachael
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Paul Keeley
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Ken
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Jane Daly
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Julia's Mother
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Greg Grunberg
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Kevin
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Sabra Williams
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Annie
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Rose Rollins
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Ellie
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Sasha Alexander
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Melissa Meade
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Tracy Middendorf
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Ashley
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Aaron Paul
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Rick Meade
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Kathryn Fiore
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Party Goer
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Colleen Crozier
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Party Goer
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Sean O'Bryan
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Party Goer
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Bruce French
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Minister
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Ellen Bry
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Lindsey's Mother
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Patrick Pankhurst
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Lindsey's Father
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Tony Guma
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Jim
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James Shanklin
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Hospital Chaplain
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Anne Betancourt
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Nurse Sally
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Antonietta De Lorenzo
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Roadblock Driver
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Andrea Sartoretti
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Roadblock Driver
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Antonio Del Prete
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Vatican Video Room Guard
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Francesco De Vito
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Greeting Priest
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Giorgio Marchesi
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Vatican Gate Guard
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Niccolò Senni
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Vatican Gate Guard
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Paolo Bonacelli
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Monsignore
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David Waters
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IMF Officer
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Michael G. Kehoe
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Hospital Employee
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Timothy Omundson
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IMF Agent
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José Zúñiga
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IMF Agent Pete
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William Francis McGuire
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IMF Head of Security
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Michelle Arthur
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Airline Worker
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Barney Cheng
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Janitor
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George Cheung
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Shanghai Game Player (uncredited)
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Brandon Molale
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Torturer (uncredited)
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Simon Rhee
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Chinese Guard at Hengshan Lu Building (uncredited)
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Marcus Young
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Chinese Guard (uncredited)
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Jerry Trimble
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Davian's Thug (uncredited)
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Alex Kurtzman
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Party Guest (uncredited)
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Roberto Orci
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Party Guest (uncredited)
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